The work presents new insights into the Quaternary evolution north of the mouth of the Amazon River, in the coastal plain of Amapá, from sedimentological data, high resolution seismic, C14 dating, and historical cartography that allowed the reconstruction of part of the North Cape region. Ancient river systems are identified below a paleosurface of the Pre-Flandrian transgression, representative of an incision when sea level was 20 m below current. The Pre-Flandrian incision surface was recognized in the seismic sequence. In the sedimentary facies, the deposits of sea-level fluctuations in the Quaternary were recognized corresponding to the Comowine phase identified on French Guiana and Suriname coasts. Most lakes developed during the Holocene, and are residues of ancient drainages that cut through the coastal plain. The record in historical charts from the 18th century suggests that the Botos lake represents a large channel that separated Carpori Island from the mainland. The work also allowed the identification of an Upper Pleistocene paleo surface in the interior of the coastal plain of Amapá.